Phospho-GABRB1 (S434) Antibody (PACO00289)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO00289
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-GABRB1 (S434) Antibody |
Antibody SKU: | PACO00289 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat, Monkey |
Immunogen: | synthesized peptide derived from human GABAA RBeta1 around the phosphorylation site of S434. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GABRB1; Gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor subunit beta-1 |
UniProt Protein Function: | GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily. |
UniProt Protein Details: | Protein type:Channel, chloride; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ion channel; Channel, ligand-gated Chromosomal Location of Human Ortholog: 4p12 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:chloride channel activity; GABA-A receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity Biological Process: synaptic transmission; transport; ion transport; signal transduction; transmembrane transport |
NCBI Summary: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008] |
UniProt Code: | P18505 |
NCBI GenInfo Identifier: | 194097327 |
NCBI Gene ID: | 2560 |
NCBI Accession: | NP_000803.2 |
UniProt Related Accession: | P18505 |
Molecular Weight: | ~ 54kDa |
NCBI Full Name: | gamma-aminobutyric acid receptor subunit beta-1 |
NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor subunit beta1 |
NCBI Official Symbol: | GABRB1 |
NCBI Official Synonym Symbols: | EIEE45 |
NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-1 |
UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-1 |
UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-1 |
UniProt Gene Name: | GABRB1 |
UniProt Entry Name: | GBRB1_HUMAN |