Phospho-EPHA7 (Y791) Antibody (PACO02652)
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주문- SKU:
- PACO02652
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | Phospho-EPHA7 (Y791) Antibody |
Antibody SKU: | PACO02652 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human EphA7 around the phosphorylation site of Y791. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | EPHA7; EHK3; HEK11; Ephrin type-A receptor 7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11 |
UniProt Protein Function: | EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains. |
UniProt Protein Details: | Protein type:Kinase, protein; EC 2.7.10.1; Protein kinase, TK; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; Eph family Chromosomal Location of Human Ortholog: 6q16.1 Cellular Component: plasma membrane Molecular Function:axon guidance receptor activity; chemorepellent activity; GPI-linked ephrin receptor activity; protein binding; protein-tyrosine kinase activity Biological Process: brain development; branching morphogenesis of a nerve; ephrin receptor signaling pathway; negative chemotaxis; phosphorylation; positive regulation of neuron apoptosis; regulation of caspase activity; regulation of cell-cell adhesion; regulation of peptidyl-tyrosine phosphorylation; regulation of protein amino acid autophosphorylation |
NCBI Summary: | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | Q15375 |
NCBI GenInfo Identifier: | 146345416 |
NCBI Gene ID: | 2045 |
NCBI Accession: | Q15375.3 |
UniProt Secondary Accession: | Q15375,Q59G40, Q5VTU0, Q8N368, Q9H124, A0AUX7, B2R8W1 B7ZLJ9, B7ZLK0, |
UniProt Related Accession: | Q15375 |
Molecular Weight: | 50,521 Da |
NCBI Full Name: | Ephrin type-A receptor 7 |
NCBI Synonym Full Names: | EPH receptor A7 |
NCBI Official Symbol: | EPHA7 |
NCBI Official Synonym Symbols: | EHK3; EK11; EHK-3; HEK11 |
NCBI Protein Information: | ephrin type-A receptor 7 |
UniProt Protein Name: | Ephrin type-A receptor 7 |
UniProt Synonym Protein Names: | EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11 |
Protein Family: | Ephrin type-A receptor |
UniProt Gene Name: | EPHA7 |
UniProt Entry Name: | EPHA7_HUMAN |