Phospho-AQP2 (S256) Antibody (PACO04160)
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주문- SKU:
- PACO04160
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | Phospho-AQP2 (S256) Antibody |
Antibody SKU: | PACO04160 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human AQP2 around the phosphorylation site of S256. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | AQP2; Aquaporin-2; AQP-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct |
UniProt Protein Function: | AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family. |
UniProt Protein Details: | Protein type:Transporter, aquaporin family; Membrane protein, integral; Channel, misc.; Transporter; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 12q12-q13 Cellular Component: recycling endosome; protein complex; clathrin-coated vesicle; membrane; rough endoplasmic reticulum; integral to plasma membrane; lysosome; basolateral plasma membrane; early endosome; apical plasma membrane; plasma membrane; trans-Golgi network Molecular Function:water transporter activity; glycerol transmembrane transporter activity; actin binding; water channel activity; PDZ domain binding; glycerol channel activity Biological Process: glycerol transport; actin filament depolymerization; cellular water homeostasis; response to glucagon stimulus; apoptosis; water transport; response to lithium ion; cellular response to water deprivation; response to lipopolysaccharide; female pregnancy; excretion; response to salt stress; response to starvation; hyperosmotic response; renal water transport; renal water homeostasis; response to calcium ion; positive regulation of calcium ion transport; transmembrane transport; aging Disease: Diabetes Insipidus, Nephrogenic, Autosomal |
NCBI Summary: | This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008] |
UniProt Code: | P41181 |
NCBI GenInfo Identifier: | 728874 |
NCBI Gene ID: | 359 |
NCBI Accession: | P41181.1 |
UniProt Related Accession: | P41181 |
Molecular Weight: | |
NCBI Full Name: | Aquaporin-2 |
NCBI Synonym Full Names: | aquaporin 2 |
NCBI Official Symbol: | AQP2 |
NCBI Official Synonym Symbols: | AQP-CD; WCH-CD |
NCBI Protein Information: | aquaporin-2 |
UniProt Protein Name: | Aquaporin-2 |
UniProt Synonym Protein Names: | ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct |
UniProt Gene Name: | AQP2 |
UniProt Entry Name: | AQP2_HUMAN |