PHKG1 Antibody (PACO20226)
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주문- SKU:
- PACO20226
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PHKG1 Antibody (PACO20226) |
Antibody SKU: | PACO20226 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human PHKG1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20226(PHKG1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Mouse skeletal muscle tissue, Primary antibody: PACO20226(PHKG1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20226(PHKG1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | phosphorylase kinase, γ 1 |
UniProt Protein Function: | PHKG1: a Ca(2+)/calmodulin-dependent protein kinase of the PHK family. Phosphorylase kinase is a polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. |
UniProt Protein Details: | Protein type:EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; EC 2.7.11.26; EC 2.7.11.19; CAMK group; PHK family Chromosomal Location of Human Ortholog: 7p11.2 Cellular Component: cytosol Biological Process: glycogen catabolic process |
NCBI Summary: | This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
UniProt Code: | Q16816 |
NCBI GenInfo Identifier: | 2833281 |
NCBI Gene ID: | 5260 |
NCBI Accession: | Q16816.3 |
UniProt Secondary Accession: | Q16816,Q75LP5, B7Z1D0, F5H2S1, |
UniProt Related Accession: | Q16816 |
Molecular Weight: | 48,867 Da |
NCBI Full Name: | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform |
NCBI Synonym Full Names: | phosphorylase kinase catalytic subunit gamma 1 |
NCBI Official Symbol: | PHKG1 |
NCBI Official Synonym Symbols: | PHKG |
NCBI Protein Information: | phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform |
UniProt Protein Name: | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform |
UniProt Synonym Protein Names: | Phosphorylase kinase subunit gamma-1; Serine/threonine-protein kinase PHKG1 (EC:2.7.11.1, EC:2.7.11.26) |
Protein Family: | Phosphorylase b kinase |
UniProt Gene Name: | PHKG1 |
UniProt Entry Name: | PHKG1_HUMAN |