PGLYRP1 Antibody (PACO20219)
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주문- SKU:
- PACO20219
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PGLYRP1 Antibody (PACO20219) |
Antibody SKU: | PACO20219 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human PGLYRP1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20219(PGLYRP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20219(PGLYRP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Peptidoglycan recognition protein is a protein that in humans is encoded by the PGLYRP1gene. Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. |
Synonyms: | peptidoglycan recognition protein 1 |
UniProt Protein Function: | PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Apoptosis; Receptor, misc.; Secreted Chromosomal Location of Human Ortholog: 19q13.2-q13.3 Cellular Component: extracellular region Molecular Function:peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process |
UniProt Code: | O75594 |
NCBI GenInfo Identifier: | 18202143 |
NCBI Gene ID: | 8993 |
NCBI Accession: | O75594.1 |
UniProt Secondary Accession: | O75594,Q4VB36, |
UniProt Related Accession: | O75594 |
Molecular Weight: | |
NCBI Full Name: | Peptidoglycan recognition protein 1 |
NCBI Synonym Full Names: | peptidoglycan recognition protein 1 |
NCBI Official Symbol: | PGLYRP1 |
NCBI Official Synonym Symbols: | PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L |
NCBI Protein Information: | peptidoglycan recognition protein 1; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) |
UniProt Protein Name: | Peptidoglycan recognition protein 1 |
UniProt Synonym Protein Names: | Peptidoglycan recognition protein short; PGRP-S |
Protein Family: | Peptidoglycan recognition protein |
UniProt Gene Name: | PGLYRP1 |
UniProt Entry Name: | PGRP1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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