PEX11B Antibody (PACO28886)
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주문- SKU:
- PACO28886
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PEX11B Antibody (PACO28886) |
Antibody SKU: | PACO28886 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Peroxisomal membrane protein 11B protein (9-228AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: PEX11B antibody at 10µg/ml Lane 1: 293T whole cell lysate Lane 2: Hela whole cell lysate Lane 3: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 29, 27 kDa Observed band size: 27 kDa . | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO28886 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO28886 at dilution of 1:100. |
Background: | Involved in peroxisomal proliferation (PubMed:9792670). May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane (PubMed:12618434). Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455). |
Synonyms: | Peroxisomal membrane protein 11B (Peroxin-11B) (Peroxisomal biogenesis factor 11B) (Protein PEX11 homolog beta) (PEX11-beta), PEX11B |
UniProt Protein Function: | PEX11B: Involved in peroxisomal proliferation. May regulate peroxisomes division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Belongs to the peroxin-11 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.1 Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; protein complex; membrane; mitochondrion; peroxisome Molecular Function:protein binding; protein homodimerization activity Biological Process: peroxisome fission; peroxisome organization and biogenesis; signal transduction; protein homooligomerization Disease: Peroxisome Biogenesis Disorder 14b |
NCBI Summary: | The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012] |
UniProt Code: | O96011 |
NCBI GenInfo Identifier: | 296317239 |
NCBI Gene ID: | 8799 |
NCBI Accession: | NP_001171724.1 |
UniProt Related Accession: | O96011 |
Molecular Weight: | ~ 28kDa |
NCBI Full Name: | peroxisomal membrane protein 11B isoform 2 |
NCBI Synonym Full Names: | peroxisomal biogenesis factor 11 beta |
NCBI Official Symbol: | PEX11B |
NCBI Official Synonym Symbols: | PEX14B; PEX11-BETA |
NCBI Protein Information: | peroxisomal membrane protein 11B |
UniProt Protein Name: | Peroxisomal membrane protein 11B |
UniProt Synonym Protein Names: | Peroxin-11B; Peroxisomal biogenesis factor 11B; Protein PEX11 homolog beta |
UniProt Gene Name: | PEX11B |
UniProt Entry Name: | PX11B_HUMAN |