PDLIM1 Antibody (PACO23719)
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주문- SKU:
- PACO23719
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PDLIM1 Antibody (PACO23719) |
Antibody SKU: | PACO23719 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human PDLIM1. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, COLO205 cells, 293 cells, HepG2 cells and HUVEC cells, using PDLIM1 antibody. | |
Immunofluorescence analysis of HepG2 cells, using PDLIM1 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human heart tissue using PDLIM1 antibody. |
Background: | Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. |
Synonyms: | C-terminal LIM domain protein 1; CLP36; Elfin; LIM domain protein CLP-36; PDL1 |
UniProt Protein Function: | CLIM1: a cytoskeletal adaptor protein that bring other proteins to the cytoskeleton. Interacts with alpha-actinins 1, 2 and 4. Recruits the Clik1 kinase to actin stress fibers in nonmuscle cells. Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: transcription factor complex; cytoskeleton; focal adhesion; cytoplasm Molecular Function:zinc ion binding; transcription coactivator activity Biological Process: regulation of transcription, DNA-dependent; response to hypoxia; response to oxidative stress |
NCBI Summary: | This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012] |
UniProt Code: | O00151 |
NCBI GenInfo Identifier: | 20178312 |
NCBI Gene ID: | 9124 |
NCBI Accession: | O00151.4 |
UniProt Secondary Accession: | O00151,Q5VZH5, Q9BPZ9, B2RBS6, |
UniProt Related Accession: | O00151 |
Molecular Weight: | 329 |
NCBI Full Name: | PDZ and LIM domain protein 1 |
NCBI Synonym Full Names: | PDZ and LIM domain 1 |
NCBI Official Symbol: | PDLIM1 |
NCBI Official Synonym Symbols: | CLIM1; CLP36; CLP-36; hCLIM1; HEL-S-112 |
NCBI Protein Information: | PDZ and LIM domain protein 1; elfin; LIM domain protein CLP-36; epididymis secretory protein Li 112; carboxyl terminal LIM domain protein 1 |
UniProt Protein Name: | PDZ and LIM domain protein 1 |
UniProt Synonym Protein Names: | C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36 |
Protein Family: | PDZ and LIM domain protein |
UniProt Gene Name: | PDLIM1 |
UniProt Entry Name: | PDLI1_HUMAN |
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