PCOLCE Antibody (PACO63791)
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주문- SKU:
- PACO63791
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PCOLCE Antibody (PACO63791) |
Antibody SKU: | PACO63791 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Procollagen C-endopeptidase enhancer 1 protein (169-449AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO63791 diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. |
Synonyms: | Procollagen C-endopeptidase enhancer 1 (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I procollagen COOH-terminal proteinase enhancer), PCOLCE, PCPE1 |
UniProt Protein Function: | Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. |
NCBI Summary: | Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15113 |
NCBI GenInfo Identifier: | 6919941 |
NCBI Gene ID: | 5118 |
NCBI Accession: | Q15113.2 |
UniProt Secondary Accession: | Q15113,O14550, B2R9E1, |
UniProt Related Accession: | Q15113 |
Molecular Weight: | 47,972 Da |
NCBI Full Name: | Procollagen C-endopeptidase enhancer 1 |
NCBI Synonym Full Names: | procollagen C-endopeptidase enhancer |
NCBI Official Symbol: | PCOLCE |
NCBI Official Synonym Symbols: | PCPE; PCPE1; PCPE-1 |
NCBI Protein Information: | procollagen C-endopeptidase enhancer 1 |
UniProt Protein Name: | Procollagen C-endopeptidase enhancer 1 |
UniProt Synonym Protein Names: | Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer |
Protein Family: | Procollagen C-endopeptidase enhancer |
UniProt Gene Name: | PCOLCE |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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