P2RY1 Antibody (PACO54034)
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주문- SKU:
- PACO54034
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | P2RY1 Antibody (PACO54034) |
Antibody SKU: | PACO54034 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human P2Y purinoceptor 1 protein (329-373AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO54034 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO54034 at dilution of 1:100. |
Background: | Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. |
Synonyms: | P2Y purinoceptor 1 (P2Y1) (ATP receptor) (Purinergic receptor), P2RY1 |
UniProt Protein Function: | P2RY1: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q25.2 Cellular Component: cell surface; dendrite; integral to plasma membrane; plasma membrane; postsynaptic membrane Molecular Function:ATP-activated nucleotide receptor activity; protein binding; purinergic nucleotide receptor activity, G-protein coupled; receptor activity Biological Process: cell surface receptor linked signal transduction; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; positive regulation of protein amino acid phosphorylation |
NCBI Summary: | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P47900 |
NCBI GenInfo Identifier: | 1352692 |
NCBI Gene ID: | 5028 |
NCBI Accession: | P47900.1 |
UniProt Related Accession: | P47900 |
Molecular Weight: | 42,072 Da |
NCBI Full Name: | P2Y purinoceptor 1 |
NCBI Synonym Full Names: | purinergic receptor P2Y1 |
NCBI Official Symbol: | P2RY1 |
NCBI Official Synonym Symbols: | P2Y1 |
NCBI Protein Information: | P2Y purinoceptor 1 |
UniProt Protein Name: | P2Y purinoceptor 1 |
UniProt Synonym Protein Names: | ATP receptor; Purinergic receptor |
Protein Family: | P2Y purinoceptor |
UniProt Gene Name: | P2RY1 |
UniProt Entry Name: | P2RY1_HUMAN |
Antibodies | ELISA Kits |
Anti-P2RY1 Antibody (CAB7706) | Human P2RY1(PURINERGIC RECEPTOR P2Y, G PROTEIN) ELISA Kit |
P2RY1 Antibody (PACO11040) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |