P2RX3 Antibody (PACO01924)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO01924
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | P2RX3 Antibody |
Antibody SKU: | PACO01924 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the Internal region of human P2X3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor |
UniProt Protein Function: | P2X3: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral Chromosomal Location of Human Ortholog: 11q12 Cellular Component: Golgi apparatus; cell soma; rough endoplasmic reticulum; integral to plasma membrane; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex; lipid raft Molecular Function:ATP binding; purinergic nucleotide receptor activity; ATP-gated cation channel activity Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; generation of action potential; regulation of synaptic plasticity; positive regulation of calcium-mediated signaling; signal transduction; response to ATP; response to carbohydrate stimulus; behavioral response to pain; transport; response to heat; response to mechanical stimulus; response to hypoxia; neuromuscular synaptic transmission; response to cold; protein homooligomerization |
NCBI Summary: | This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017] |
UniProt Code: | P56373 |
NCBI GenInfo Identifier: | 259016295 |
NCBI Gene ID: | 5024 |
NCBI Accession: | |
UniProt Related Accession: | P56373 |
Molecular Weight: | |
NCBI Full Name: | P2X purinoceptor 3 |
NCBI Synonym Full Names: | purinergic receptor P2X 3 |
NCBI Official Symbol: | P2RX3 |
NCBI Official Synonym Symbols: | P2X3 |
NCBI Protein Information: | P2X purinoceptor 3 |
UniProt Protein Name: | P2X purinoceptor 3 |
UniProt Synonym Protein Names: | ATP receptor; Purinergic receptor |
UniProt Gene Name: | P2RX3 |
UniProt Entry Name: | P2RX3_HUMAN |