OXCT1 Antibody (PACO13600)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13600
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | OXCT1 Antibody (PACO13600) |
Antibody SKU: | PACO13600 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SCOT |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | 3-oxoacid, CoA transferase 1;OXCT1;OXCT;SCOT ; |
UniProt Protein Function: | OXCT1: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. Defects in OXCT1 are a cause of succinyl-CoA-3-ketoacid- CoA transferase deficiency (SCOTD). A disorder of ketone body metabolism, characterized by episodic ketoacidosis. Patients are usually asymptomatic between episodes. Belongs to the 3-oxoacid CoA-transferase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Transferase; Lipid Metabolism - synthesis and degradation of ketone bodies; EC 2.8.3.5 Chromosomal Location of Human Ortholog: 5p13.1 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:3-oxoacid CoA-transferase activity Biological Process: ketone body catabolic process; ketone body metabolic process Disease: Succinyl-coa:3-oxoacid Coa Transferase Deficiency |
NCBI Summary: | This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008] |
UniProt Code: | P55809 |
NCBI GenInfo Identifier: | 2492998 |
NCBI Gene ID: | 5019 |
NCBI Accession: | P55809.1 |
UniProt Secondary Accession: | P55809,B2R5V2, B7Z528, |
UniProt Related Accession: | P55809 |
Molecular Weight: | 13,358 Da |
NCBI Full Name: | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial |
NCBI Synonym Full Names: | 3-oxoacid CoA-transferase 1 |
NCBI Official Symbol: | OXCT1 |
NCBI Official Synonym Symbols: | OXCT; SCOT |
NCBI Protein Information: | succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial |
UniProt Protein Name: | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial |
UniProt Synonym Protein Names: | 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s |
Protein Family: | Succinyl-CoA:3-ketoacid coenzyme A transferase |
UniProt Gene Name: | OXCT1 |
UniProt Entry Name: | SCOT1_HUMAN |