OPTC Antibody (PACO63363)
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주문- SKU:
- PACO63363
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | OPTC Antibody (PACO63363) |
Antibody SKU: | PACO63363 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Opticin protein (20-332AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO63363 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO63363 diluted at 1:100 and staining in paraffin-embedded human eye tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Binds collagen fibrils. |
Synonyms: | Opticin (Oculoglycan), OPTC, OPT |
UniProt Protein Function: | OPTC: Binds collagen fibrils. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: proteinaceous extracellular matrix Molecular Function:extracellular matrix structural constituent Biological Process: negative regulation of angiogenesis |
NCBI Summary: | Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq] |
UniProt Code: | Q9UBM4 |
NCBI GenInfo Identifier: | 5777529 |
NCBI Gene ID: | 26254 |
NCBI Accession: | |
UniProt Secondary Accession: | Q9UBM4,Q5T2G4, |
UniProt Related Accession: | Q9UBM4 |
Molecular Weight: | 37,261 Da |
NCBI Full Name: | opticin |
NCBI Synonym Full Names: | opticin |
NCBI Official Symbol: | OPTC |
NCBI Official Synonym Symbols: | OPT; OPTC |
NCBI Protein Information: | opticin; oculoglycan |
UniProt Protein Name: | Opticin |
UniProt Synonym Protein Names: | Oculoglycan |
Protein Family: | Opticin |
UniProt Gene Name: | OPTC |
UniProt Entry Name: | OPT_HUMAN |
Antibodies | ELISA Kits |
Anti-OPTC Antibody (CAB16514) | Human Opticin / OPTC ELISA Kit |
OPTC Antibody (PACO11009) | Human Opticin (OPTC) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |