OPLAH Antibody (PACO13708)
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주문- SKU:
- PACO13708
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | OPLAH Antibody (PACO13708) |
Antibody SKU: | PACO13708 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human OPLAH |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | 5-oxoprolinase (ATP-hydrolysing);OPLAH;5-Opase;DKFZp434H244;OPLA ; |
UniProt Protein Function: | OPLAH: Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Defects in OPLAH are the cause of 5-oxoprolinase deficiency (OPLAHD). A disorder characterized by calcium oxalate/carbonate urolithiasis, and excessive urinary 5- oxo-L-proline. Affected individuals have recurrent episodes of vomiting, diarrhea, and abdominal pain. Belongs to the oxoprolinase family. |
UniProt Protein Details: | Protein type:EC 3.5.2.9; Hydrolase; Other Amino Acids Metabolism - glutathione Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytosol Molecular Function:5-oxoprolinase (ATP-hydrolyzing) activity Biological Process: glutathione biosynthetic process Disease: 5-oxoprolinase Deficiency |
NCBI Summary: | The protein encoded by this gene acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD). [provided by RefSeq, Jun 2012] |
UniProt Code: | O14841 |
NCBI GenInfo Identifier: | 59802978 |
NCBI Gene ID: | 26873 |
NCBI Accession: | O14841.3 |
UniProt Secondary Accession: | O14841,Q75W65, Q9Y4Q0, A5PKY8, |
UniProt Related Accession: | O14841 |
Molecular Weight: | 137kDa |
NCBI Full Name: | 5-oxoprolinase |
NCBI Synonym Full Names: | 5-oxoprolinase (ATP-hydrolysing) |
NCBI Official Symbol: | OPLAH |
NCBI Official Synonym Symbols: | OPLA; OPLAHD; 5-Opase |
NCBI Protein Information: | 5-oxoprolinase |
UniProt Protein Name: | 5-oxoprolinase |
UniProt Synonym Protein Names: | 5-oxo-L-prolinase; 5-OPase; Pyroglutamase |
UniProt Gene Name: | OPLAH |