NPRL2 Antibody (PACO13543)
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주문- SKU:
- PACO13543
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NPRL2 Antibody (PACO13543) |
Antibody SKU: | PACO13543 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human NPR2L,TUSC4 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.320°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | 44kd; |
UniProt Protein Function: | NPRL2: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs. Belongs to the NPR2 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Tumor suppressor; Inhibitor Chromosomal Location of Human Ortholog: 3p21.3 Molecular Function:protein binding; GTPase activator activity; protein kinase activity Biological Process: negative regulation of kinase activity; protein amino acid phosphorylation; positive regulation of GTPase activity |
UniProt Code: | Q8WTW4 |
NCBI GenInfo Identifier: | 47117604 |
NCBI Gene ID: | 10641 |
NCBI Accession: | Q8WTW4.2 |
UniProt Secondary Accession: | Q8WTW4,Q6FGS2, Q9Y249, Q9Y497, A8K831, |
UniProt Related Accession: | Q8WTW4 |
Molecular Weight: | Observed MW 40kDaCalculated MW 23kDa/43kDa |
NCBI Full Name: | Nitrogen permease regulator 2-like protein |
NCBI Synonym Full Names: | nitrogen permease regulator-like 2 (S. cerevisiae) |
NCBI Official Symbol: | NPRL2 |
NCBI Official Synonym Symbols: | NPR2; NPR2L; TUSC4 |
NCBI Protein Information: | nitrogen permease regulator 2-like protein; G21 protein; 2810446G01Rik; gene 21 protein; NPR2-like protein; tumor suppressor candidate 4; homologous to yeast nitrogen permease (candidate tumor suppressor) |
UniProt Protein Name: | Nitrogen permease regulator 2-like protein |
UniProt Synonym Protein Names: | Gene 21 protein; G21 protein; Tumor suppressor candidate 4 |
Protein Family: | Nitrogen permease regulator 2-like protein |
UniProt Gene Name: | NPRL2 |
UniProt Entry Name: | NPRL2_HUMAN |