NOXA1 Antibody (PACO46074)
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주문- SKU:
- PACO46074
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NOXA1 Antibody (PACO46074) |
Antibody SKU: | PACO46074 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human NADPH oxidase activator 1 protein (150-313AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: NOXA1 antibody at 2 µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51, 52, 46 kDa. Observed band size: 51 kDa.. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO46074 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO46074 at dilution of 1:100. |
Background: | Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. |
Synonyms: | NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox), NOXA1, P51NOX |
UniProt Protein Function: | NOXA1: Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. Belongs to the NCF2/NOXA1 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Activator Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: cytoplasm; NADPH oxidase complex Molecular Function:protein binding; enzyme binding; Rac GTPase binding; superoxide-generating NADPH oxidase activator activity; SH3 domain binding Biological Process: positive regulation of catalytic activity; superoxide metabolic process; regulation of hydrogen peroxide metabolic process |
NCBI Summary: | This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q86UR1 |
NCBI GenInfo Identifier: | 74759404 |
NCBI Gene ID: | 10811 |
NCBI Accession: | Q86UR1.1 |
UniProt Secondary Accession: | Q86UR1,Q8CJ00, A7E3N7, |
UniProt Related Accession: | Q86UR1 |
Molecular Weight: | 45,245 Da |
NCBI Full Name: | NADPH oxidase activator 1 |
NCBI Synonym Full Names: | NADPH oxidase activator 1 |
NCBI Official Symbol: | NOXA1 |
NCBI Official Synonym Symbols: | p51NOX; NY-CO-31; SDCCAG31 |
NCBI Protein Information: | NADPH oxidase activator 1; p51-nox; Nox activator 1; antigen NY-CO-31; NCF2-like protein; p67phox-like factor; inhibitory NADPH oxidase activator 1; serologically defined colon cancer antigen 31 |
UniProt Protein Name: | NADPH oxidase activator 1 |
UniProt Synonym Protein Names: | Antigen NY-CO-31; NCF2-like protein; P67phox-like factor; p51-nox |
Protein Family: | NADPH oxidase activator |
UniProt Gene Name: | NOXA1 |
UniProt Entry Name: | NOXA1_HUMAN |
Antibodies |
Anti-NOXA1 Antibody (CAB13844) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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