NOL3 Antibody (PACO15483)
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주문- SKU:
- PACO15483
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NOL3 Antibody (PACO15483) |
Antibody SKU: | PACO15483 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human NOL3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15483(NOL3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15483(NOL3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum. |
Synonyms: | nucleolar protein 3 (apoptosis repressor with CARD domain) |
UniProt Protein Function: | Isoform 1: May be involved in RNA splicing. |
NCBI Summary: | This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
UniProt Code: | O60936 |
NCBI GenInfo Identifier: | 20455079 |
NCBI Gene ID: | 8996 |
NCBI Accession: | O60936.1 |
UniProt Secondary Accession: | O60936,O60937, B4DFL0, |
UniProt Related Accession: | O60936 |
Molecular Weight: | 29,355 Da |
NCBI Full Name: | Nucleolar protein 3 |
NCBI Synonym Full Names: | nucleolar protein 3 (apoptosis repressor with CARD domain) |
NCBI Official Symbol: | NOL3 |
NCBI Official Synonym Symbols: | ARC; FCM; MYP; NOP; NOP30 |
NCBI Protein Information: | nucleolar protein 3; nucleolar protein of 30 kDa; muscle-enriched cytoplasmic protein |
UniProt Protein Name: | Nucleolar protein 3 |
UniProt Synonym Protein Names: | Apoptosis repressor with CARD; Muscle-enriched cytoplasmic protein; Myp; Nucleolar protein of 30 kDa; Nop30 |
Protein Family: | Nucleolar protein |
UniProt Gene Name: | NOL3 |
UniProt Entry Name: | NOL3_HUMAN |