NFATC2IP Antibody (PACO10827)
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주문- SKU:
- PACO10827
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NFATC2IP Antibody (PACO10827) |
Antibody SKU: | PACO10827 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human NFATC2IP |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein;NFATC2IP;FLJ14639;MGC126790;MGC138387 ;NIP45 |
UniProt Protein Function: | NFATC2IP: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytoplasm; nucleus Biological Process: cytokine production; positive regulation of transcription from RNA polymerase II promoter |
UniProt Code: | Q8NCF5 |
NCBI GenInfo Identifier: | 51873914 |
NCBI Gene ID: | 84901 |
NCBI Accession: | AAH80628.1 |
UniProt Secondary Accession: | Q8NCF5,O09130, Q6AYG7, |
UniProt Related Accession: | Q8NCF5 |
Molecular Weight: | 45,817 Da |
NCBI Full Name: | NFATC2IP protein, partial |
NCBI Synonym Full Names: | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
NCBI Official Symbol: | NFATC2IP |
NCBI Official Synonym Symbols: | ESC2; NIP45; RAD60 |
NCBI Protein Information: | NFATC2-interacting protein; 45 kDa NFAT-interacting protein; 45 kDa NF-AT-interacting protein; nuclear factor of activated T-cells, cytoplasmic 2-interacting protein |
UniProt Protein Name: | NFATC2-interacting protein |
UniProt Synonym Protein Names: | 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein |
UniProt Gene Name: | NFATC2IP |
UniProt Entry Name: | NF2IP_HUMAN |