Neurocalcin-Delta/NCALD Recombinant Protein (RPES0259)

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SKU:
RPES0259
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Neurocalcin-Delta/NCALD Recombinant Protein

Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.

Product Name:Neurocalcin-Delta/NCALD Recombinant Protein (RPES0259)
Product Code:RPES0259
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Neurocalcin-Delta, NCALD
Accession:P61601
Sequence:Met 1-Phe193
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:24.4 kDa
AP Mol Mass:20 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 40% Glycerol, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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