NEU4 Antibody (PACO13696)
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주문- SKU:
- PACO13696
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NEU4 Antibody (PACO13696) |
Antibody SKU: | PACO13696 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Human NEU4 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | sialidase 4;NEU4;MGC102757;MGC18222 ; |
UniProt Protein Function: | NEU4: May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N- acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids. Belongs to the glycosyl hydrolase 33 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid Metabolism - sphingolipid; EC 3.2.1.18; Hydrolase; Glycan Metabolism - other glycan degradation Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: lysosomal lumen; organelle inner membrane; mitochondrion; lysosome Molecular Function:protein binding; exo-alpha-sialidase activity Biological Process: oligosaccharide catabolic process; cellular protein metabolic process; sphingolipid metabolic process; dolichol-linked oligosaccharide biosynthetic process; ganglioside catabolic process; glycosphingolipid metabolic process; protein amino acid N-linked glycosylation via asparagine; glycoprotein catabolic process; post-translational protein modification |
NCBI Summary: | The protein encoded by this gene belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Nov 2009] |
UniProt Code: | Q8WWR8 |
NCBI GenInfo Identifier: | 262527265 |
NCBI Gene ID: | 129807 |
NCBI Accession: | NP_001161072.1 |
UniProt Secondary Accession: | Q8WWR8,Q96D64, A8K056, J3KNJ5, |
UniProt Related Accession: | Q8WWR8 |
Molecular Weight: | 53,066 Da |
NCBI Full Name: | sialidase-4 isoform 3 |
NCBI Synonym Full Names: | neuraminidase 4 |
NCBI Official Symbol: | NEU4 |
NCBI Protein Information: | sialidase-4 |
UniProt Protein Name: | Sialidase-4 |
UniProt Synonym Protein Names: | N-acetyl-alpha-neuraminidase 4 |
Protein Family: | Sialidase |
UniProt Gene Name: | NEU4 |
UniProt Entry Name: | NEUR4_HUMAN |