NDUFS3 Antibody (PACO44839)
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주문- SKU:
- PACO44839
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NDUFS3 Antibody (PACO44839) |
Antibody SKU: | PACO44839 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial protein (37-264AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: NDUFS3 antibody at 1.98µg/ml. Lane 1: Mouse brain tissue. Lane 2: Mouse skeletal muscle tissue. Lane 3: Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 31, 15 kDa. Observed band size: 31 kDa.. | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO44839 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO44839 at dilution of 1:100. |
Background: | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). |
Synonyms: | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit), NDUFS3 |
UniProt Protein Function: | NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family. |
UniProt Protein Details: | Protein type:EC 1.6.5.3; Oxidoreductase; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 11p11.11 Cellular Component: mitochondrial matrix; mitochondrial membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleus Molecular Function:NADH dehydrogenase activity; protein binding Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; negative regulation of cell growth; substantia nigra development Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency |
NCBI Summary: | This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009] |
UniProt Code: | O75489 |
NCBI GenInfo Identifier: | 6166589 |
NCBI Gene ID: | 4722 |
NCBI Accession: | O75489.1 |
UniProt Secondary Accession: | O75489,Q9UNQ8, B2R9J1, B4DFM8, |
UniProt Related Accession: | O75489 |
Molecular Weight: | 14,679 Da |
NCBI Full Name: | NADH dehydrogenase |
NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase core subunit S3 |
NCBI Official Symbol: | NDUFS3 |
NCBI Official Synonym Symbols: | CI-30 |
NCBI Protein Information: | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
UniProt Protein Name: | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
UniProt Synonym Protein Names: | Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit |
UniProt Gene Name: | NDUFS3 |
UniProt Entry Name: | NDUS3_HUMAN |
Antibodies |
Anti-NDUFS3 Antibody (CAB8013)[KO Validated] |
Anti-NDUFS3 Antibody (CAB4602) |
NDUFS3 Antibody (PACO02925) |
NDUFS3 Antibody (PACO10795) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |