NCR1 Antibody (PACO19415)
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주문- SKU:
- PACO19415
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | NCR1 Antibody (PACO19415) |
Antibody SKU: | PACO19415 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human NCR1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19415(NCR1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: PACO19415(NCR1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human Lymphoma tissue using PACO19415(NCR1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. NCR1 has also been designated as CD335 (cluster of differentiation 335). Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Interacts with CD247 and FCER1G. Selectively expressed by both resting and activated NK cells. |
Synonyms: | natural cytotoxicity triggering receptor 1 |
UniProt Protein Function: | NCR1: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Belongs to the natural cytotoxicity receptor (NCR) family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc.; Apoptosis Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: SWI/SNF complex; integral to plasma membrane Molecular Function:receptor signaling protein activity Biological Process: regulation of natural killer cell mediated cytotoxicity; natural killer cell activation; cellular defense response; signal transduction |
UniProt Code: | O76036 |
NCBI GenInfo Identifier: | 47605775 |
NCBI Gene ID: | 9437 |
NCBI Accession: | O76036.1 |
UniProt Secondary Accession: | O76036,O76016, O76017, O76018, B0V3L2, B0V3L3, B0V3L4 B0V3L5, B8JL03, |
UniProt Related Accession: | O76036 |
Molecular Weight: | 34,409 Da |
NCBI Full Name: | Natural cytotoxicity triggering receptor 1 |
NCBI Synonym Full Names: | natural cytotoxicity triggering receptor 1 |
NCBI Official Symbol: | NCR1 |
NCBI Official Synonym Symbols: | LY94; CD335; NKP46; NK-p46 |
NCBI Protein Information: | natural cytotoxicity triggering receptor 1; NK cell-activating receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural killer cell p46-related protein |
UniProt Protein Name: | Natural cytotoxicity triggering receptor 1 |
UniProt Synonym Protein Names: | Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD_antigen: CD335 |
Protein Family: | Niemann-Pick type C-related protein |
UniProt Gene Name: | NCR1 |
UniProt Entry Name: | NCTR1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |