MTIF3 Antibody (PACO45153)
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주문- SKU:
- PACO45153
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MTIF3 Antibody (PACO45153) |
Antibody SKU: | PACO45153 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Translation initiation factor IF-3, mitochondrial protein (1-278AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MTIF3 antibody at 1.15 µg/ml. Lane 1: Mouse small intestine tissue. Lane 2: Rat heart tissue. Lane 3: Mouse liver tissue. Lane 4: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 32 kDa. Observed band size: 32, 100, 75 kDa.. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO45153 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO45153 at dilution of 1:100. |
Background: | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. |
Synonyms: | Translation initiation factor IF-3, mitochondrial (IF-3(Mt)) (IF-3Mt) (IF3(mt)) (IF3mt), MTIF3 |
UniProt Protein Function: | MTIF3: IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. Belongs to the IF-3 family. |
UniProt Protein Details: | Protein type:Translation initiation; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 13q12.2 Cellular Component: mitochondrion Molecular Function:protein binding; ribosomal small subunit binding; translation factor activity, nucleic acid binding; translation initiation factor activity Biological Process: mitochondrial translation; organelle organization and biogenesis; ribosome disassembly |
NCBI Summary: | This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q9H2K0 |
NCBI GenInfo Identifier: | 317373570 |
NCBI Gene ID: | 219402 |
NCBI Accession: | Q9H2K0.4 |
UniProt Secondary Accession: | Q9H2K0,Q05BL8, Q5W0V0, Q86X68, |
UniProt Related Accession: | Q9H2K0 |
Molecular Weight: | 31,725 Da |
NCBI Full Name: | Translation initiation factor IF-3, mitochondrial |
NCBI Synonym Full Names: | mitochondrial translational initiation factor 3 |
NCBI Official Symbol: | MTIF3 |
NCBI Official Synonym Symbols: | IF3mt |
NCBI Protein Information: | translation initiation factor IF-3, mitochondrial |
UniProt Protein Name: | Translation initiation factor IF-3, mitochondrial |
UniProt Gene Name: | MTIF3 |
UniProt Entry Name: | IF3M_HUMAN |
Antibodies |
Anti-MTIF3 Antibody (CAB12615) |
Anti-MTIF3 Antibody (CAB8524) |
MTIF3 Antibody (PACO02689) |
MTIF3 Antibody (PACO10642) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |