MRPL54 Antibody (PACO23352)
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주문- SKU:
- PACO23352
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRPL54 Antibody (PACO23352) |
Antibody SKU: | PACO23352 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human MRPL54. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, using MRPL54 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using MRPL54 antibody. |
Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. |
Synonyms: | 39S ribosomal protein 54; mitochondrial; L54mt; mitochondrial ribosomal protein L54; MRP-L54 |
UniProt Protein Function: | MRPL54: |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: mitochondrial inner membrane; ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6P161 |
NCBI GenInfo Identifier: | 74737109 |
NCBI Gene ID: | 116541 |
NCBI Accession: | Q6P161.1 |
UniProt Related Accession: | Q6P161 |
Molecular Weight: | 15,819 Da |
NCBI Full Name: | 39S ribosomal protein L54, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein L54 |
NCBI Official Symbol: | MRPL54 |
NCBI Official Synonym Symbols: | L54mt; MRP-L54 |
NCBI Protein Information: | 39S ribosomal protein L54, mitochondrial |
UniProt Protein Name: | 39S ribosomal protein L54, mitochondrial |
Protein Family: | 39S ribosomal protein |
UniProt Gene Name: | MRPL54 |
UniProt Entry Name: | RM54_HUMAN |