MRPL39 Antibody (PACO16703)
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주문- SKU:
- PACO16703
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRPL39 Antibody (PACO16703) |
Antibody SKU: | PACO16703 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human MRPL39 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16703(MRPL39 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, K562 cells, 231 cells, hela cells, Primary antibody: PACO16703(MRPL39 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16703(MRPL39 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. |
Synonyms: | mitochondrial ribosomal protein L39 |
UniProt Protein Function: | MRPL39: 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Translation; Ribosomal Chromosomal Location of Human Ortholog: 21q21.3 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:ligase activity, forming aminoacyl-tRNA and related compounds; proline-tRNA ligase activity; RNA binding Biological Process: mitochondrial genome maintenance; prolyl-tRNA aminoacylation; tRNA aminoacylation for protein translation |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYK5 |
NCBI GenInfo Identifier: | 296452977 |
NCBI Gene ID: | 54148 |
NCBI Accession: | Q9NYK5.3 |
UniProt Secondary Accession: | Q9NYK5,Q32Q74, Q5QTR3, Q96Q65, Q9BSQ7, Q9BZV6, Q9NX44 C9JYA5, |
UniProt Related Accession: | Q9NYK5 |
Molecular Weight: | 40,458 Da |
NCBI Full Name: | 39S ribosomal protein L39, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein L39 |
NCBI Official Symbol: | MRPL39 |
NCBI Official Synonym Symbols: | L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92 |
NCBI Protein Information: | 39S ribosomal protein L39, mitochondrial |
UniProt Protein Name: | 39S ribosomal protein L39, mitochondrial |
UniProt Synonym Protein Names: | 39S ribosomal protein L5, mitochondrial; L5mt; MRP-L5 |
Protein Family: | 39S ribosomal protein |
UniProt Gene Name: | MRPL39 |
UniProt Entry Name: | RM39_HUMAN |