MRGPRX1 Antibody (PACO20039)
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주문- SKU:
- PACO20039
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRGPRX1 Antibody (PACO20039) |
Antibody SKU: | PACO20039 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human MRGPRX1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20039(MRGPRX1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20039(MRGPRX1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. |
Synonyms: | MAS-related GPR, member X1 |
UniProt Code: | Q96LB2 |
NCBI GenInfo Identifier: | 125660451 |
NCBI Gene ID: | 259249 |
NCBI Accession: | NP_671732 |
UniProt Related Accession: | Q96LB2 |
Molecular Weight: | 36kDa |
NCBI Full Name: | mas-related G-protein coupled receptor member X1 |
NCBI Synonym Full Names: | MAS related GPR family member X1 |
NCBI Official Symbol: | MRGPRX1 |
NCBI Official Synonym Symbols: | GPCR; MGRG2; MRGX1; SNSR4 |
NCBI Protein Information: | mas-related G-protein coupled receptor member X1 |
UniProt Protein Name: | Serine/threonine-protein kinase MST4 |
UniProt Synonym Protein Names: | Mammalian STE20-like protein kinase 4; MST-4; Mst3 and SOK1-related kinase; STE20-like kinase MST4; Serine/threonine-protein kinase MASK |
UniProt Gene Name: | MST4 |
UniProt Entry Name: | MST4_HUMAN |