Mouse TNFSF4/OX40L Recombinant Protein (RPES2487)

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SKU:
RPES2487
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
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Description

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Mouse TNFSF4/OX40L Recombinant Protein

OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.

Product Name:Mouse TNFSF4/OX40L Recombinant Protein (RPES2487)
Product Code:RPES2487
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4
Accession:P43488
Sequence: Ser51-Leu198
Fusion tag:N-8His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Ser51-Leu198 is expressed with a 8His tag at the N-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:17.7 kDa
AP Mol Mass:20-23 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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