Mouse NgR/RTN4R Recombinant Protein (RPES2467)

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SKU:
RPES2467
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
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Description

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Mouse NgR/RTN4R Recombinant Protein

Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.

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