Mouse LAMP2/CD107b Recombinant Protein (RPES4504)
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주문- SKU:
- RPES4504
- Product type:
- Recombinant Protein
- Host species:
- HEK293 Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
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Mouse LAMP2/CD107b Recombinant Protein
LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
| Product Name: | Mouse LAMP2/CD107b Recombinant Protein (RPES4504) |
| Product Code: | RPES4504 |
| Size: | 50µg |
| Species: | Mouse |
| Expressed Host: | HEK293 Cells |
| Synonyms: | CD107b,Lamp-2,Lamp-2a,Lamp-2b,Lamp-2c,LampII,LGP-B,Mac3 |
| Accession: | P17047-1 |
| Sequence: | Leu 26-Asn 379 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the mouse LAMP2 (P17047-1) extracellular domain (Leu 26-Asn 379) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus. |
| Purity: | > 97 % as determined by SDS-PAGE |
| Mol Mass: | 40.6 kDa |
| AP Mol Mass: | 70-80 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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