Mouse Cadherin-3/CDH3 Recombinant Protein (RPES4929)

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SKU:
RPES4929
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
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Description

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Mouse Cadherin-3/CDH3 Recombinant Protein

Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

Product Name:Mouse Cadherin-3/CDH3 Recombinant Protein (RPES4929)
Product Code:RPES4929
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Cadherin-3, Placental cadherin, P-cadherin, Cdh3
Accession:P10287
Sequence: Glu100-Gly647
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.
Purity:> 90 % as determined by SDS-PAGE
Mol Mass:87.5 kDa
AP Mol Mass:120 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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