MID2 Antibody (PACO45186)
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주문- SKU:
- PACO45186
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MID2 Antibody (PACO45186) |
Antibody SKU: | PACO45186 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Probable E3 ubiquitin-protein ligase MID2 protein (506-735AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45186 at dilution of 1:100. | |
Immunofluorescent analysis of MCF-7 cells using PACO45186 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May play a role in microtubule stabilization. |
Synonyms: | Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1), MID2, FXY2 RNF60 TRIM1 |
UniProt Protein Function: | MID2: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] |
UniProt Protein Details: | Protein type:Microtubule-binding; EC 6.3.2.-; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: Xq22.3 Cellular Component: microtubule Molecular Function:microtubule binding; phosphoprotein binding; protein heterodimerization activity; protein homodimerization activity Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity Disease: Mental Retardation, X-linked 101 |
NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] |
UniProt Code: | Q9UJV3 |
NCBI GenInfo Identifier: | 294862489 |
NCBI Gene ID: | 11043 |
NCBI Accession: | Q9UJV3.3 |
UniProt Secondary Accession: | Q9UJV3,Q5JYF5, Q8WWK1, Q9UJR9, A6NEL8, A6PVI5, |
UniProt Related Accession: | Q9UJV3 |
Molecular Weight: | 79,865 Da |
NCBI Full Name: | Probable E3 ubiquitin-protein ligase MID2 |
NCBI Synonym Full Names: | midline 2 |
NCBI Official Symbol: | MID2 |
NCBI Official Synonym Symbols: | FXY2; RNF60; TRIM1; MRX101 |
NCBI Protein Information: | probable E3 ubiquitin-protein ligase MID2 |
UniProt Protein Name: | Probable E3 ubiquitin-protein ligase MID2 |
UniProt Synonym Protein Names: | Midin-2; Midline defect 2; Midline-2; RING finger protein 60; Tripartite motif-containing protein 1 |
Protein Family: | Cell wall integrity sensor |
UniProt Gene Name: | MID2 |
UniProt Entry Name: | TRIM1_HUMAN |