MGST2 Antibody (PACO51706)
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주문- SKU:
- PACO51706
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MGST2 Antibody (PACO51706) |
Antibody SKU: | PACO51706 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Microsomal glutathione S-transferase 2 protein (27-57AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO51706 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO51706 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione. |
Synonyms: | Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18) (Microsomal GST-II), MGST2, GST2 |
UniProt Protein Function: | MGST2: Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4- dinitrobenzene with reduced glutathione. Belongs to the MAPEG family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transferase; Membrane protein, integral; Other Amino Acids Metabolism - glutathione; Endoplasmic reticulum; EC 2.5.1.18; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 4q28.3 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bound organelle; nuclear envelope; plasma membrane Molecular Function:glutathione peroxidase activity; glutathione transferase activity; leukotriene-C4 synthase activity Biological Process: glutathione biosynthetic process; leukotriene biosynthetic process; xenobiotic metabolic process |
NCBI Summary: | The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011] |
UniProt Code: | Q99735 |
NCBI GenInfo Identifier: | 2842764 |
NCBI Gene ID: | 4258 |
NCBI Accession: | Q99735.1 |
UniProt Secondary Accession: | Q99735,Q7Z5B8, D6RBB5, |
UniProt Related Accession: | Q99735 |
Molecular Weight: | 8,359 Da |
NCBI Full Name: | Microsomal glutathione S-transferase 2 |
NCBI Synonym Full Names: | microsomal glutathione S-transferase 2 |
NCBI Official Symbol: | MGST2 |
NCBI Official Synonym Symbols: | GST2; MGST-II |
NCBI Protein Information: | microsomal glutathione S-transferase 2 |
UniProt Protein Name: | Microsomal glutathione S-transferase 2 |
UniProt Synonym Protein Names: | Microsomal GST-II |
Protein Family: | Microsomal glutathione S-transferase |
UniProt Gene Name: | MGST2 |
UniProt Entry Name: | MGST2_HUMAN |