MC4R Antibody (PACO18198)
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주문- SKU:
- PACO18198
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MC4R Antibody (PACO18198) |
Antibody SKU: | PACO18198 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human MC4R |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18198(MC4R Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18198(MC4R Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity |
Synonyms: | Melanocortin 4 receptor |
UniProt Protein Function: | MC4R: receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. A G-protein coupled receptor that stimulates adenylate cyclase. Defects are a cause of autosomal dominant obesity |
UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 18q21.32 Cellular Component: plasma membrane Molecular Function:melanocortin receptor activity; melanocyte stimulating hormone receptor activity; neuropeptide binding; protein binding; ubiquitin protein ligase binding Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of bone resorption; positive regulation of cAMP biosynthetic process Disease: Obesity |
NCBI Summary: | The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010] |
UniProt Code: | P32245 |
NCBI GenInfo Identifier: | 60392672 |
NCBI Gene ID: | 4160 |
NCBI Accession: | P32245.2 |
UniProt Secondary Accession: | P32245,Q16317, Q3MIJ6, B2RAC3, |
UniProt Related Accession: | P32245 |
Molecular Weight: | 37kDa |
NCBI Full Name: | Melanocortin receptor 4 |
NCBI Synonym Full Names: | melanocortin 4 receptor |
NCBI Official Symbol: | MC4R |
NCBI Protein Information: | melanocortin receptor 4 |
UniProt Protein Name: | Melanocortin receptor 4 |
Protein Family: | Melanocortin receptor |
UniProt Gene Name: | MC4R |
Antibodies | ELISA Kits |
Anti-MC4R Antibody (CAB10228) | Human MC4R / Melanocortin receptor 4 ELISA Kit |
MC4R Antibody (PACO04303) | Human Melanocortin receptor 4 (MC4R) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |