MATR3 Antibody (PACO16655)
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주문- SKU:
- PACO16655
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MATR3 Antibody (PACO16655) |
Antibody SKU: | PACO16655 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human MATR3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-6: 293T cells, K562 cells, hela cells, 231 cells, Jurkat cells, NIH/3T3 cells, Primary antibody: PACO16655(MATR3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds. |
Background: | This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. |
Synonyms: | matrin 3 |
UniProt Protein Function: | matrin 3: an acidic protein that is a component of the nuclear matrix. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. |
UniProt Protein Details: | Protein type:RNA-binding; RNA processing Chromosomal Location of Human Ortholog: 5q31.2 Cellular Component: membrane; nuclear inner membrane; nucleoplasm Molecular Function:protein binding; structural molecule activity Disease: Amyotrophic Lateral Sclerosis 21 |
NCBI Summary: | This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013] |
UniProt Code: | P43243 |
NCBI GenInfo Identifier: | 12643409 |
NCBI Gene ID: | 9782 |
NCBI Accession: | P43243.2 |
UniProt Secondary Accession: | P43243,Q9UHW0, Q9UQ27, B7ZAV5, D3DQC3, |
UniProt Related Accession: | P43243 |
Molecular Weight: | 62,576 Da |
NCBI Full Name: | Matrin-3 |
NCBI Synonym Full Names: | matrin 3 |
NCBI Official Symbol: | MATR3 |
NCBI Official Synonym Symbols: | MPD2; ALS21; VCPDM |
NCBI Protein Information: | matrin-3 |
UniProt Protein Name: | Matrin-3 |
Protein Family: | Matrin |
UniProt Gene Name: | MATR3 |
UniProt Entry Name: | MATR3_HUMAN |