MAFF Antibody (PACO18183)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO18183
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MAFF Antibody (PACO18183) |
Antibody SKU: | PACO18183 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human MAFF |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: PACO18183(MAFF Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
Background: | The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. |
Synonyms: | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
UniProt Protein Function: | MAFF: Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response. Belongs to the bZIP family. Maf subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: mitochondrion; nucleoplasm; nucleus Biological Process: blood coagulation; parturition; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] |
UniProt Code: | Q9ULX9 |
NCBI GenInfo Identifier: | 21542145 |
NCBI Gene ID: | 23764 |
NCBI Accession: | Q9ULX9.2 |
UniProt Secondary Accession: | Q9ULX9,Q9Y525, B4DV49, |
UniProt Related Accession: | Q9ULX9 |
Molecular Weight: | 14,569 Da |
NCBI Full Name: | Transcription factor MafF |
NCBI Synonym Full Names: | MAF bZIP transcription factor F |
NCBI Official Symbol: | MAFF |
NCBI Official Synonym Symbols: | U-MAF; hMafF |
NCBI Protein Information: | transcription factor MafF |
UniProt Protein Name: | Transcription factor MafF |
UniProt Synonym Protein Names: | U-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F |
Protein Family: | MaFF-interacting protein |
UniProt Gene Name: | MAFF |
UniProt Entry Name: | MAFF_HUMAN |
Antibodies | ELISA Kits |
Anti-MAFF Antibody (CAB12920) | MAFF Transcription Factor Activity Assay |
MAFF Antibody (PACO03737) | |
MAFF Antibody (PACO10332) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |