Macaca nemestrina PCSK9 Recombinant Protein (RPES3577)

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SKU:
RPES3577
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Macaca nemestrina
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Description

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Macaca nemestrina PCSK9 Recombinant Protein

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

Product Name:Macaca nemestrina PCSK9 Recombinant Protein (RPES3577)
Product Code:RPES3577
Size:10µg
Species:Macaca nemestrina
Expressed Host:Human Cells
Synonyms:Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PC9, Subtilisin/Kexin-Like Protease PC9, PCSK9
Accession:A8T662
Sequence:Gln31-Gln152&Ser153-Gln692
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Macaca nemestrina PCSK9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln152&Ser153-Gln692 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:14&59 kDa
AP Mol Mass:18&70 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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