LSS Antibody (PACO44443)
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주문- SKU:
- PACO44443
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LSS Antibody (PACO44443) |
Antibody SKU: | PACO44443 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Lanosterol synthase protein (1-300AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: LSS antibody at 0.76µg/ml. Lane 1: PC-3 whole cell lysate. Lane 2: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 84, 75, 83 kDa. Observed band size: 84 kDa.. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO44443 at dilution of 1:100. |
Background: | Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. |
Synonyms: | Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC), LSS, OSC |
UniProt Protein Function: | LSS: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Belongs to the terpene cyclase/mutase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - steroid biosynthesis; EC 5.4.99.7; Isomerase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum membrane; membrane; lipid particle Molecular Function:lanosterol synthase activity Biological Process: steroid metabolic process; cholesterol biosynthetic process Disease: Cataract 44 |
NCBI Summary: | The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009] |
UniProt Code: | P48449 |
NCBI GenInfo Identifier: | 1352387 |
NCBI Gene ID: | 4047 |
NCBI Accession: | P48449.1 |
UniProt Secondary Accession: | P48449,Q8IYL6, Q9UEZ1, B4DJZ9, D3DSN0, E9PEI9, G5E9Q9 |
UniProt Related Accession: | P48449 |
Molecular Weight: | 82,199 Da |
NCBI Full Name: | Lanosterol synthase |
NCBI Synonym Full Names: | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
NCBI Official Symbol: | LSS |
NCBI Official Synonym Symbols: | OSC |
NCBI Protein Information: | lanosterol synthase; hOSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase |
UniProt Protein Name: | Lanosterol synthase |
UniProt Synonym Protein Names: | 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC |
Protein Family: | Lysostaphin |
UniProt Gene Name: | LSS |
UniProt Entry Name: | ERG7_HUMAN |
Antibodies | ELISA Kits |
Anti-LSS Antibody (CAB6930) | Human LSS / Lanosterol synthase ELISA Kit |
LSS Antibody (PACO10307) | Human Lanosterol synthase (LSS) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |