UniProt Protein Function: | LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: Xq21.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; lipid binding Biological Process: G-protein coupled receptor protein signaling pathway |
NCBI Summary: | This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009] |
UniProt Code: | Q99677 |
NCBI GenInfo Identifier: | 2495042 |
NCBI Gene ID: | 2846 |
NCBI Accession: | Q99677.1 |
UniProt Secondary Accession: | Q99677,O15132, Q502U9, Q6NSP5, B2RAC7, |
UniProt Related Accession: | Q99677 |
Molecular Weight: | 41,895 Da |
NCBI Full Name: | Lysophosphatidic acid receptor 4 |
NCBI Synonym Full Names: | lysophosphatidic acid receptor 4 |
NCBI Official Symbol: | LPAR4 |
NCBI Official Synonym Symbols: | LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE |
NCBI Protein Information: | lysophosphatidic acid receptor 4; G protein-coupled receptor 23; G-protein coupled receptor 23; LPA receptor 4; LPA-4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9 |
UniProt Protein Name: | Lysophosphatidic acid receptor 4 |
UniProt Synonym Protein Names: | G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9 |
Protein Family: | Lysophosphatidic acid receptor |
UniProt Gene Name: | LPAR4 |
UniProt Entry Name: | LPAR4_HUMAN |