LGALS3BP Antibody (PACO16617)
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주문- SKU:
- PACO16617
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LGALS3BP Antibody (PACO16617) |
Antibody SKU: | PACO16617 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human LGALS3BP |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16617(LGALS3BP Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16617(LGALS3BP Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. |
Synonyms: | lectin, galactoside-binding, soluble, 3 binding protein |
UniProt Protein Function: | LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: extracellular matrix; extracellular region; extracellular space Biological Process: cellular defense response; platelet degranulation; signal transduction |
NCBI Summary: | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q08380 |
NCBI GenInfo Identifier: | 47115668 |
NCBI Gene ID: | 3959 |
NCBI Accession: | Q08380.1 |
UniProt Secondary Accession: | Q08380,Q7M4S0, Q9UCH8, Q9UCH9, Q9UCI0, |
UniProt Related Accession: | Q08380 |
Molecular Weight: | 65kDa |
NCBI Full Name: | Galectin-3-binding protein |
NCBI Synonym Full Names: | galectin 3 binding protein |
NCBI Official Symbol: | LGALS3BP |
NCBI Official Synonym Symbols: | 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B |
NCBI Protein Information: | galectin-3-binding protein |
UniProt Protein Name: | Galectin-3-binding protein |
UniProt Synonym Protein Names: | Basement membrane autoantigen p105; Lectin galactoside-binding soluble 3-binding protein; Mac-2-binding protein; MAC2BP; Mac-2 BP; Tumor-associated antigen 90K |
Protein Family: | Galectin-3-binding protein |
UniProt Gene Name: | LGALS3BP |
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