LEFTY1/LEFTY2 Antibody (PACO06923)
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주문- SKU:
- PACO06923
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LEFTY1/LEFTY2 Antibody (PACO06923) |
Antibody SKU: | PACO06923 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from the C-terminal region of human Lefty. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of HepG2-UV cells using Lefty Polyclonal Antibody. | |
Western Blot analysis of HEPG2-UV cells using Lefty Polyclonal Antibody. |
Synonyms: | LEFTY1; LEFTB; LEFTYB; Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B; LEFTY2; EBAF; LEFTA; LEFTYA; TGFB4; PSEC0024; Left-right determination factor 2; Endometrial bleeding-associated factor; Left-ri |
UniProt Protein Function: | LEFTY1: Required for left-right axis determination as a regulator of LEFTY2 and NODAL. Belongs to the TGF-beta family. |
UniProt Protein Details: | Protein type:Cytokine; Ligand, receptor tyrosine kinase; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 1q42.1 Cellular Component: extracellular space Molecular Function:cytokine activity; transforming growth factor beta receptor binding Biological Process: cell development; determination of left/right symmetry; heart morphogenesis; negative regulation of transcription from RNA polymerase II promoter; regulation of apoptosis; regulation of MAPKKK cascade; transforming growth factor beta receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75610 |
NCBI GenInfo Identifier: | 13124321 |
NCBI Gene ID: | 10637 |
NCBI Accession: | O75610.1 |
UniProt Secondary Accession: | O75610,Q53H67, Q5TE94, B2R7U0, |
UniProt Related Accession: | O75610 |
Molecular Weight: | 40,880 Da |
NCBI Full Name: | Left-right determination factor 1 |
NCBI Synonym Full Names: | left-right determination factor 1 |
NCBI Official Symbol: | LEFTY1 |
NCBI Official Synonym Symbols: | LEFTB; LEFTYB |
NCBI Protein Information: | left-right determination factor 1 |
UniProt Protein Name: | Left-right determination factor 1 |
UniProt Synonym Protein Names: | Left-right determination factor B; Protein lefty-1; Protein lefty-B |
Protein Family: | Left-right determination factor |
UniProt Gene Name: | LEFTY1 |
UniProt Entry Name: | LFTY1_HUMAN |