KLK5 Antibody (PACO18127)
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주문- SKU:
- PACO18127
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLK5 Antibody (PACO18127) |
Antibody SKU: | PACO18127 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human KLK5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: PACO18127(KLK5 Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18127(KLK5 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. |
Synonyms: | kallikrein-related peptidase 5 |
UniProt Protein Function: | KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily. |
UniProt Protein Details: | Protein type:EC 3.4.21.-; Protease; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: extracellular space Molecular Function:peptidase activity; protein binding; serine-type peptidase activity; serine-type endopeptidase activity Biological Process: epidermis development; positive regulation of G-protein coupled receptor protein signaling pathway; proteolysis |
NCBI Summary: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y337 |
NCBI GenInfo Identifier: | 296434569 |
NCBI Gene ID: | 25818 |
NCBI Accession: | Q9Y337.2 |
UniProt Secondary Accession: | Q9Y337,Q53ZR3, Q9HBG8, |
UniProt Related Accession: | Q9Y337 |
Molecular Weight: | 293 |
NCBI Full Name: | Kallikrein-5 |
NCBI Synonym Full Names: | kallikrein-related peptidase 5 |
NCBI Official Symbol: | KLK5 |
NCBI Official Synonym Symbols: | SCTE; KLKL2; KLK-L2 |
NCBI Protein Information: | kallikrein-5; kallikrein 5; kallikrein-like protein 2; stratum corneum tryptic enzyme |
UniProt Protein Name: | Kallikrein-5 |
UniProt Synonym Protein Names: | Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme |
Protein Family: | Kallikrein |
UniProt Gene Name: | KLK5 |
UniProt Entry Name: | KLK5_HUMAN |
Antibodies | ELISA Kits |
Anti-KLK5 Antibody (CAB14863) | Human Kallikrein-5 (KLK5) ELISA Kit |
Anti-KLK5 Antibody (CAB2991) | |
KLK5 Antibody (PACO10144) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |