KLHL9 Antibody (PACO16595)
- SKU:
- PACO16595
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLHL9 Antibody (PACO16595) |
Antibody SKU: | PACO16595 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human KLHL9 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, SKOV3 cells, Jurkat cells, Primary antibody: PACO16595(KLHL9 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
Background: | The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL9 (kelch-like 9) is a 617 amino acid, protein containing one BACK (BTB/kelch associated) domain, six kelch repeats and a BTB/POZ domain. KLHL9 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapters of an E3 ubiquitin-protein ligase complex with CUL-3. |
Synonyms: | kelch-like family member 9 |
UniProt Protein Function: | KLHL9: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 9p22 Cellular Component: midbody Molecular Function:ubiquitin-protein ligase activity Biological Process: mitosis; cytokinesis; protein ubiquitination |
UniProt Code: | Q9P2J3 |
NCBI GenInfo Identifier: | 51338828 |
NCBI Gene ID: | 55958 |
NCBI Accession: | Q9P2J3.2 |
UniProt Secondary Accession: | Q9P2J3,Q8TCQ2, |
UniProt Related Accession: | Q9P2J3 |
Molecular Weight: | 69,429 Da |
NCBI Full Name: | Kelch-like protein 9 |
NCBI Synonym Full Names: | kelch-like family member 9 |
NCBI Official Symbol: | KLHL9 |
NCBI Protein Information: | kelch-like protein 9; kelch-like 9 |
UniProt Protein Name: | Kelch-like protein 9 |
Protein Family: | Kelch-like protein |
UniProt Gene Name: | KLHL9 |
UniProt Entry Name: | KLHL9_HUMAN |
Antibodies |
Anti-KLHL9 Antibody (CAB10149) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |