KLHL8 Antibody (PACO19909)
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주문- SKU:
- PACO19909
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLHL8 Antibody (PACO19909) |
Antibody SKU: | PACO19909 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human KLHL8 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19909(KLHL8 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO19909(KLHL8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19909(KLHL8 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Kelch-like protein 8 is a protein that in humans is encoded by the KLHL8 gene. Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. |
Synonyms: | kelch-like family member 8 |
UniProt Protein Function: | KLHL8: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. Component of the BCR(KLHL8) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL8 and RBX1. Interacts with RAPSN |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q22.1 Cellular Component: nucleoplasm Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process; protein ubiquitination |
UniProt Code: | Q9P2G9 |
NCBI GenInfo Identifier: | 635172825 |
NCBI Gene ID: | 57563 |
NCBI Accession: | NP_001278932.1 |
UniProt Related Accession: | Q9P2G9 |
Molecular Weight: | 60kDa; 68kDa |
NCBI Full Name: | kelch-like protein 8 isoform 1 |
NCBI Synonym Full Names: | kelch like family member 8 |
NCBI Official Symbol: | KLHL8 |
NCBI Protein Information: | kelch-like protein 8 |
UniProt Protein Name: | Kelch-like protein 8 |
Protein Family: | Kelch-like protein |
UniProt Gene Name: | KLHL8 |
UniProt Entry Name: | KLHL8_HUMAN |
Antibodies |
Anti-KLHL8 Antibody (CAB14917) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |