KIF20B Antibody (PACO22429)
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주문- SKU:
- PACO22429
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KIF20B Antibody (PACO22429) |
Antibody SKU: | PACO22429 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from C-terminal of human MPHOSPH9. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from A549 cells, using MPHOSPH9 antibody. |
Background: | Plus-end-directed motor enzyme that is required for completion of cytokinesis. |
Synonyms: | M-phase phosphoprotein 9; MPP9; |
UniProt Protein Function: | Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). |
UniProt Code: | Q96Q89 |
NCBI GenInfo Identifier: | 546231677 |
NCBI Gene ID: | 9585 |
NCBI Accession: | NP_001271188.1 |
UniProt Secondary Accession: | Q96Q89,O43277, Q09471, Q2KQ73, Q32NE1, Q561V3, Q58EX8 Q5T9M8, Q5T9M9, Q5T9N0, Q5T9N1, A8MXM7, |
UniProt Related Accession: | Q96Q89 |
Molecular Weight: | 59,621 Da |
NCBI Full Name: | kinesin-like protein KIF20B isoform 1 |
NCBI Synonym Full Names: | kinesin family member 20B |
NCBI Official Symbol: | KIF20B |
NCBI Official Synonym Symbols: | CT90; MPP1; KRMP1; MPP-1; MPHOSPH1 |
NCBI Protein Information: | kinesin-like protein KIF20B |
UniProt Protein Name: | Kinesin-like protein KIF20B |
UniProt Synonym Protein Names: | Cancer/testis antigen 90; CT90; Kinesin family member 20B |
Protein Family: | Mitochondrial-processing peptidase |
UniProt Gene Name: | KIF20B |