KIF1B Antibody (PACO44387)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO44387
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | KIF1B Antibody (PACO44387) |
Antibody SKU: | PACO44387 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Kinesin-like protein KIF1B protein (1547-1816AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO44387 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44387 at dilution of 1:100. |
Background: | Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. |
Synonyms: | Kinesin-like protein KIF1B (Klp), KIF1B, KIAA0591 KIAA1448 |
UniProt Protein Function: | KIF1B: a member of the kinesin motor protein family. Motor for anterograde transport of mitochondria. May play a role in synaptic vesicle transport. Has a microtubule plus end-directed motility. Aberrant expression seen in neuroblastoma. Mutated in Charcot-Marie-Tooth disease. |
UniProt Protein Details: | Protein type:Microtubule-binding; Motor Chromosomal Location of Human Ortholog: 1p36.2 Cellular Component: microtubule; kinesin complex; neuron projection; microtubule associated complex; cytoplasmic vesicle membrane; mitochondrion; cytoplasmic vesicle Molecular Function:protein binding; kinesin binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding Biological Process: vesicle-mediated transport; apoptosis; metabolic process; neuromuscular synaptic transmission; nerve-nerve synaptic transmission; cytoskeleton-dependent intracellular transport; anterograde axon cargo transport; microtubule-based movement; mitochondrion transport along microtubule Disease: Charcot-marie-tooth Disease, Axonal, Type 2a1; Neuroblastoma, Susceptibility To; Pheochromocytoma |
NCBI Summary: | This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60333 |
NCBI GenInfo Identifier: | 116242605 |
NCBI Gene ID: | 23095 |
NCBI Accession: | O60333.5 |
UniProt Secondary Accession: | O60333,Q4VXC3, Q4VXC4, Q4VXC5, Q4VXC6, Q96Q94, Q9BV80 Q9P280, A6NFS8, A6NKQ4, |
UniProt Related Accession: | O60333 |
Molecular Weight: | 1816 |
NCBI Full Name: | Kinesin-like protein KIF1B |
NCBI Synonym Full Names: | kinesin family member 1B |
NCBI Official Symbol: | KIF1B |
NCBI Official Synonym Symbols: | KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1 |
NCBI Protein Information: | kinesin-like protein KIF1B; kinesin superfamily protein KIF1B |
UniProt Protein Name: | Kinesin-like protein KIF1B |
Protein Family: | Kinesin-like protein |
UniProt Gene Name: | KIF1B |
UniProt Entry Name: | KIF1B_HUMAN |