KIF11 Antibody (PACO06451)
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주문- SKU:
- PACO06451
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | KIF11 Antibody (PACO06451) |
Antibody SKU: | PACO06451 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from human Eg5 around the non-phosphorylation site of T926. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of K562 cells using Eg5 Polyclonal Antibody. | |
Western Blot analysis of COLO205 cells using Eg5 Polyclonal Antibody. |
Synonyms: | KIF11; EG5; KNSL1; TRIP5; Kinesin-like protein KIF11; Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5 |
UniProt Protein Function: | KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus. |
UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 10q24.1 Cellular Component: spindle pole; kinesin complex; microtubule; membrane; spindle microtubule; cytoplasm; spindle; cytosol Molecular Function:plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; protein complex binding; microtubule motor activity; protein kinase binding; ATP binding Biological Process: mitosis; mitotic centrosome separation; mitotic spindle organization and biogenesis; cell division; metabolic process; regulation of mitotic centrosome separation; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; spindle organization and biogenesis; microtubule-based movement; chromosome segregation Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation |
NCBI Summary: | This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52732 |
NCBI GenInfo Identifier: | 116242604 |
NCBI Gene ID: | 3832 |
NCBI Accession: | P52732.2 |
UniProt Secondary Accession: | P52732,Q15716, Q5VWX0, A0AV49, B2RMV3, |
UniProt Related Accession: | P52732 |
Molecular Weight: | 119,159 Da |
NCBI Full Name: | Kinesin-like protein KIF11 |
NCBI Synonym Full Names: | kinesin family member 11 |
NCBI Official Symbol: | KIF11 |
NCBI Official Synonym Symbols: | EG5; HKSP; KNSL1; MCLMR; TRIP5 |
NCBI Protein Information: | kinesin-like protein KIF11; TR-interacting protein 5; TRIP-5; kinesin-like protein 1; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; thyroid receptor-interacting protein 5 |
UniProt Protein Name: | Kinesin-like protein KIF11 |
UniProt Synonym Protein Names: | Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5 |
Protein Family: | Kinesin-like protein |
UniProt Gene Name: | KIF11 |
UniProt Entry Name: | KIF11_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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