JUN Antibody (PACO13850)
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주문- SKU:
- PACO13850
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | JUN Antibody (PACO13850) |
Antibody SKU: | PACO13850 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human JUN |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO13850(JUN Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO13850(JUN Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. |
Synonyms: | jun proto-oncogene |
UniProt Protein Function: | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
NCBI Summary: | This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008] |
UniProt Code: | P05412 |
NCBI GenInfo Identifier: | 135298 |
NCBI Gene ID: | 3725 |
NCBI Accession: | P05412.2 |
UniProt Secondary Accession: | P05412,Q6FHM7, Q96G93, |
UniProt Related Accession: | P05412 |
Molecular Weight: | |
NCBI Full Name: | Transcription factor AP-1 |
NCBI Synonym Full Names: | jun proto-oncogene |
NCBI Official Symbol: | JUN |
NCBI Official Synonym Symbols: | AP1; AP-1; c-Jun |
NCBI Protein Information: | transcription factor AP-1 |
UniProt Protein Name: | Transcription factor AP-1 |
UniProt Synonym Protein Names: | Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 |
Protein Family: | C-Jun-amino-terminal kinase-interacting protein |
UniProt Gene Name: | JUN |
UniProt Entry Name: | JUN_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |