IVL Antibody (PACO00975)
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주문- SKU:
- PACO00975
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IVL Antibody |
Antibody SKU: | PACO00975 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the C-terminal region of human Involucrin. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | IVL; Involucrin |
UniProt Protein Function: | IVL: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Belongs to the involucrin family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cornified envelope Molecular Function:protein binding, bridging; structural molecule activity Biological Process: keratinocyte differentiation; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; keratinization; peptide cross-linking; response to UV-B |
NCBI Summary: | Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] |
UniProt Code: | P07476 |
NCBI GenInfo Identifier: | 254763301 |
NCBI Gene ID: | 3713 |
NCBI Accession: | P07476.2 |
UniProt Secondary Accession: | P07476,Q5T7P4, |
UniProt Related Accession: | P07476 |
Molecular Weight: | 68,479 Da |
NCBI Full Name: | Involucrin |
NCBI Synonym Full Names: | involucrin |
NCBI Official Symbol: | IVL |
NCBI Protein Information: | involucrin |
UniProt Protein Name: | Involucrin |
Protein Family: | Involucrin |
UniProt Gene Name: | IVL |
UniProt Entry Name: | INVO_HUMAN |