ING1 Antibody (PACO13491)
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주문- SKU:
- PACO13491
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ING1 Antibody (PACO13491) |
Antibody SKU: | PACO13491 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse |
Immunogen: | Human ING1-specific |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | inhibitor of growth family, member 1;ING1;p24ING1c;p33;p33ING1;p33ING1b;p47;p47ING1a ; |
UniProt Protein Function: | ING1: Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC); also known as squamous cell carcinoma of the head and neck. Belongs to the ING family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Tumor suppressor Chromosomal Location of Human Ortholog: 13q34 Cellular Component: cytoplasm; nucleoplasm Molecular Function:methylated histone residue binding; protein binding Disease: Squamous Cell Carcinoma, Head And Neck |
NCBI Summary: | This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UK53 |
NCBI GenInfo Identifier: | 212276438 |
NCBI Gene ID: | 3621 |
NCBI Accession: | Q9UK53.2 |
UniProt Secondary Accession: | Q9UK53,O00532, O43658, Q53ZR3, Q5T9G8, Q5T9G9, Q5T9H0 Q5T9H1, Q9H007, Q9HD98, Q9HD99, Q9NS83, |
UniProt Related Accession: | Q9UK53 |
Molecular Weight: | 29,572 Da |
NCBI Full Name: | Inhibitor of growth protein 1 |
NCBI Synonym Full Names: | inhibitor of growth family member 1 |
NCBI Official Symbol: | ING1 |
NCBI Official Synonym Symbols: | p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a |
NCBI Protein Information: | inhibitor of growth protein 1 |
UniProt Protein Name: | Inhibitor of growth protein 1 |
Protein Family: | Inhibitor of growth protein |
UniProt Gene Name: | ING1 |
UniProt Entry Name: | ING1_HUMAN |