INA Antibody (PACO18745)
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주문- SKU:
- PACO18745
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | INA Antibody (PACO18745) |
Antibody SKU: | PACO18745 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human INA |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using PACO18745(INA Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18745(INA Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. |
Synonyms: | Internexin neuronal intermediate filament protein, alpha |
UniProt Protein Function: | INA: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges. Belongs to the intermediate filament family. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 10q24.33 Cellular Component: extracellular space; intermediate filament cytoskeleton; nuclear membrane; nucleoplasm Molecular Function:structural constituent of cytoskeleton Biological Process: substantia nigra development |
NCBI Summary: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009] |
UniProt Code: | Q16352 |
NCBI GenInfo Identifier: | 20141266 |
NCBI Gene ID: | 9118 |
NCBI Accession: | Q16352.2 |
UniProt Secondary Accession: | Q16352,Q9BRC5, B1AQK0, |
UniProt Related Accession: | Q16352 |
Molecular Weight: | 55,391 Da |
NCBI Full Name: | Alpha-internexin |
NCBI Synonym Full Names: | internexin neuronal intermediate filament protein alpha |
NCBI Official Symbol: | INA |
NCBI Official Synonym Symbols: | NEF5; NF-66; TXBP-1 |
NCBI Protein Information: | alpha-internexin |
UniProt Protein Name: | Alpha-internexin |
UniProt Synonym Protein Names: | 66 kDa neurofilament protein; NF-66; Neurofilament-66; Neurofilament 5 |
Protein Family: | Immune inhibitor |
UniProt Gene Name: | INA |
UniProt Entry Name: | AINX_HUMAN |