IMMT Antibody (PACO14574)
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주문- SKU:
- PACO14574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IMMT Antibody (PACO14574) |
Antibody SKU: | PACO14574 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human IMMT |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14574(IMMT Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Raji cells, 231 cells, HepG2 cells, Hela cells, 293T cells, Primary antibody: PACO14574(IMMT Antibody) at dilution 1/270 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14574(IMMT Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.IMMT has been shown to interact with BAT2.The mitochondrial inner membrane (IM) serves as the site for ATP production by hosting the oxidative phosphorylation complex machinery most notably on the crista membranes. Disruption of the crista structure has been implicated in a variety of cardiovascular and neurodegenerative diseases. |
Synonyms: | inner membrane protein, mitochondrial |
UniProt Protein Function: | IMMT: 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 2p11.2|2 Cellular Component: mitochondrion; membrane; mitochondrial inner membrane; integral to membrane Molecular Function:protein binding Biological Process: mitochondrial calcium ion homeostasis; response to cold |
UniProt Code: | Q16891 |
NCBI GenInfo Identifier: | 29427676 |
NCBI Gene ID: | |
NCBI Accession: | Q16891.1 |
Molecular Weight: | ~ 84kDa |
NCBI Full Name: | MICOS complex subunit MIC60 |
UniProt Protein Name: | MICOS complex subunit MIC60 |
UniProt Synonym Protein Names: | Cell proliferation-inducing gene 4/52 protein; Mitochondrial inner membrane protein; Mitofilin; p87/89 |
UniProt Gene Name: | IMMT |
UniProt Entry Name: | MIC60_HUMAN |